Functio laesa

Functio laesa is a term used in medicine to refer to a loss of function[1][2] or a disturbance of function.[3]

It was identified as the fifth sign of acute inflammation by Galen,[4] who added it to the four signs identified by Celsus (tumor, rubor, calor, and dolor).

The attribution to Galen is disputed,[3] and has variously been attributed to Thomas Sydenham[5] and Rudolf Virchow.[6]

References

  1. ↑ "Dorlands Medical Dictionary:cardinal signs".
  2. ↑ "Definition: functio laesa from Online Medical Dictionary".
  3. 1 2 Rather LJ (March 1971). "Disturbance of function (functio laesa): The legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus". Bull N Y Acad Med. 47 (3): 303–22. PMC 1749862Freely accessible. PMID 5276838.
  4. ↑ Porth, Carol (2007). Essentials of pahtophysiology: concepts of altered health states. Hagerstown, MD: Lippincott Williams & Wilkins. p. 270. ISBN 0-7817-7087-4.
  5. ↑ Dormandy, Thomas (2006). The worst of evils: man's fight against pain. New Haven, Conn: Yale University Press. p. 22. ISBN 0-300-11322-6.
  6. ↑ David Lowell Strayer; Raphael Rubin (2007). Rubin's Pathology: Clinicopathologic Foundations of Medicine 5th Edition. Hagerstown, MD: Lippincott Williams & Wilkins. p. 37. ISBN 0-7817-9516-8.


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