Hydroflumethiazide
![]() | |
Clinical data | |
---|---|
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
ATC code | C03AA02 (WHO) |
Identifiers | |
| |
CAS Number |
135-09-1 ![]() |
PubChem (CID) | 3647 |
IUPHAR/BPS | 7197 |
DrugBank |
DB00774 ![]() |
ChemSpider |
3521 ![]() |
UNII |
501CFL162R ![]() |
KEGG |
D00654 ![]() |
ChEMBL |
CHEMBL1763 ![]() |
ECHA InfoCard | 100.004.704 |
Chemical and physical data | |
Formula | C8H8F3N3O4S2 |
Molar mass | 331.29 g/mol |
3D model (Jmol) | Interactive image |
| |
| |
(verify) |
Hydroflumethiazide (or Saluron) is a diuretic.
Synthesis
![](../I/m/Hydroflumethiazide_synthesis.svg.png)
Hydroflumethiazide synthesis:[1][2][3] Numerous patents, e.g., Lund et al., U.S. Patent 3,254,076 (1966 to Lövens Kemiske Fabrik).
See also
References
- ↑ Holdrege, C. T.; Babel, R. B.; Cheney, L. C. (1959). "Synthesis of Trifluoromethylated Compounds Possessing Diuretic Activity1". Journal of the American Chemical Society. 81 (18): 4807. doi:10.1021/ja01527a015.
- ↑ Close, W. J.; Swett, L. R.; Brady, L. E.; Short, J. H.; Vernsten, M. (1960). "Synthesis of Potential Diuretic Agents. I. Derivatives of 7-Sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-Dioxide". Journal of the American Chemical Society. 82 (5): 1132. doi:10.1021/ja01490a028.
- ↑ Novello, F. C.; Bell, S. C.; Abrams, E. L. A.; Ziegler, C.; Sprague, J. M. (1960). "Diuretics: 1,2,4-Benzothiadiazine-1,1-dioxides". The Journal of Organic Chemistry. 25 (6): 970. doi:10.1021/jo01076a028.
This article is issued from Wikipedia - version of the 4/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.