Mutant protein
A mutant protein is the protein product encoded by a gene with mutation.[1] Mutated protein can have single amino acid change (minor, but still in many cases significant change leading to disease) or wide-range amino acid changes by e.g. truncation of C-terminus after introducing premature stop codon.
See also
References
- ↑ Wang, Qing; Chaerkady, Raghothama; Wu, Jian; Hwang, Hee Jung; Papadopoulos, Nick; Kopelovich, Levy; Maitra, Anirban; Matthaei, Hanno; et al. (2011). "Mutant proteins as cancer-specific biomarkers". Proceedings of the National Academy of Sciences. 108 (6): 2444–9. doi:10.1073/pnas.1019203108. PMC 3038743. PMID 21248225.
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