Pheophorbide A
Names | |
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IUPAC name
(3S,4S)-9-Ethenyl-14-ethyl-21-(methoxycarbonyl)-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid | |
Identifiers | |
15664-29-6 | |
3D model (Jmol) | Interactive image |
ChEBI | CHEBI:38257 |
ChemSpider | 10343120 |
ECHA InfoCard | 100.036.110 |
EC Number | 239-738-5 |
KEGG | C18021 |
PubChem | 5323510 |
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Properties | |
C35H36N4O5 | |
Molar mass | 592.68 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Pheophorbide a is the product of chlorophyll breakdown. It is used as a photosensitizer.[1]
Photodynamic therapy (PDT) with several photosensitizers is a promising modality for the treatment of cancer. In this study, the therapeutic effect of PDT using the synthetic photosensitizer pheophorbide a (Pa-PDT) was examined in AT-84 murine oral squamous cell carcinoma (OSCC) cells.
References
- ↑ Chen, K.; et al. (2009). "Novel photosensitizer-protein nanoparticles for Photodynamic therapy: Photophysical characterization and in vitro investigations". Journal of Photochemistry and Photobiology B: Biology. 96 (1): 66–74. doi:10.1016/j.jphotobiol.2009.04.006.
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