Oryzin

Oryzin
Identifiers
EC number 3.4.21.63
CAS number 2620433
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Oryzin (EC 3.4.21.63, Aspergillus alkaline proteinase, aspergillopeptidase B, API 21, aspergillopepsin B, aspergillopepsin F, Aspergillus candidus alkaline proteinase, Aspergillus flavus alkaline proteinase, Aspergillus melleus semi-alkaline proteinase, Aspergillus oryzae alkaline proteinase, Aspergillus parasiticus alkaline proteinase, Aspergillus serine proteinase, Aspergillus sydowi alkaline proteinase, Aspergillus soya alkaline proteinase, Aspergillus melleus alkaline proteinase, Aspergillus sulphureus alkaline proteinase, prozyme, P 5380, kyorinase, seaprose S, semi-alkaline protease, sumizyme MP, prozyme 10, onoprose, onoprose SA, protease P, promelase) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins with broad specificity, and of Bz-Arg-OEt > Ac-Tyr-OEt. Does not hydrolyse peptide amides

This enzyme is a predominant extracellular alkaline endopeptidase of the mold Aspergillus oryzae.

References

  1. Nakagawa, Y. (1970). "Alkaline proteinases from Aspergillus". Methods Enzymol. 19: 581–591. doi:10.1016/0076-6879(70)19046-x.
  2. Hayashi, K.; Terada, M. (1972). "Some characteristics of hydrolysis of synthetic substrates and proteins by the alkaline proteases from Aspergillus sojae". Agric. Biol. Chem. 36: 1755–1765. doi:10.1271/bbb1961.36.1755.
  3. Turková, J.; Mikes, O.; Hayashi, K.; Danno, G.; Polgár, L. (1972). "Alkaline proteinases of the genus Aspergillus". Biochim. Biophys. Acta. 257: 257–263. doi:10.1016/0005-2795(72)90277-2. PMID 4623338.
  4. Morihara, K.; Oka, T.; Tsuzuki, H. (1974). "Comparative study of various serine alkaline proteinases from microorganisms. Esterase activity against N-acylated peptide ester substrates". Arch. Biochem. Biophys. 165: 72–79. doi:10.1016/0003-9861(74)90143-x. PMID 4441086.
  5. Spadari, S.; Subramanian, A.R.; Kalnitsky, G. (1974). "Highly restricted specificity of the serine proteinase aspergillopeptidase B". Biochim. Biophys. Acta. 359: 267–272. doi:10.1016/0005-2795(74)90224-4. PMID 4859351.
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