SoRI-9804

SoRI-9804

Names
IUPAC name N-Benzhydryl-2-phenylquinazolin-4-amine
Other names Benzhydryl-(2-phenyl-quinazolin-4-yl)-amine; 4-((Diphenylmethyl)amino)-2-phenylquinazoline
Identifiers
3D model (Jmol)	Interactive image
PubChem	9930153
InChI InChI=1S/C27H21N3/c1-4-12-20(13-5-1)25(21-14-6-2-7-15-21)29-27-23-18-10-11-19-24(23)28-26(30-27)22-16-8-3-9-17-22/h1-19,25H,(H,28,29,30) Key: LJIQXEUCYVPWRY-UHFFFAOYSA-N
SMILES C1=CC=C(C=C1)C2=NC3=CC=CC=C3C(=N2)NC(C4=CC=CC=C4)C5=CC=CC=C5
Properties
Chemical formula	C27H21N3
Molar mass	387.49 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

SoRI-9804 is a positive allosteric modulator of dopamine transporters. Unlike others in its series & traditional DRI ligands, it inhibits the release of dopamine in addition to inhibiting the reuptake of released dopamine back into the transporter.^[1]

See also

• SoRI-20041

SoRI-20040

References

1. "Studies of the biogenic amine transporters. 13. Identification of "agonist" and "antagonist" allosteric modulators of amphetamine-induced dopamine release". 329 (2). May 2009: 718–28. doi:10.1124/jpet.108.149088. PMC 2672863. PMID 19244097.