Tricin synthase

Tricin synthase
Identifiers
EC number 2.1.1.175
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Tricin synthase (EC 2.1.1.175, ROMT-17, ROMT-15, HvOMT1, ZmOMT1) is an enzyme with systematic name S-adenosyl-L-methionine:tricetin 3',5'-O-dimethyltransferase.[1][2] This enzyme catalyses the following chemical reaction

2 S-adenosyl-L-methionine + tricetin 2 S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin (overall reaction)
(1a) S-adenosyl-L-methionine + tricetin S-adenosyl-L-homocysteine + 3'-O-methyltricetin
(1b) S-adenosyl-L-methionine + 3'-O-methyltricetin S-adenosyl-L-homocysteine + 3',5'-O-dimethyltricetin

The enzymes from Oryza sativa (ROMT-15 and ROMT-17) catalyses the stepwise methylation of tricetin to its 3'-mono- and 3',5'-dimethyl ethers.

References

  1. Lee, Y.J.; Kim, B.G.; Chong, Y.; Lim, Y.; Ahn, J.H. (2008). "Cation dependent O-methyltransferases from rice". Planta. 227: 641–647. doi:10.1007/s00425-007-0646-4. PMID 17943312.
  2. Zhou JM, Fukushi Y, Wollenweber E, Ibrahim RK (2008). "Characterization of two O-methyltransferase-like genes in barley and maize". Pharm. Biol. 46: 26–34. doi:10.1080/13880200701729745.
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