Infectious pancreatic necrosis birnavirus Vp4 peptidase
Infectious pancreatic necrosis birnavirus Vp4 peptidase | |||||||||
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Identifiers | |||||||||
EC number | 3.4.21.115 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Infectious pancreatic necrosis birnavirus Vp4 peptidase (EC 3.4.21.115, infectious pancreatic necrosis virus protease, IPNV Vp4 protease, IPNV Vp4 peptidase, NS protease, NS-associated protease, Vp4 protease) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction
- Cleaves the (Ser/Thr)-Xaa-Ala-(Ser/Ala)-Gly motif in the polyprotein NH2-pVP2-VP4-VP3-COOH of infectious pancreatic necrosis virus at the pVP2-VP4 and VP4-VP3 junctions
Infectious pancreatic necrosis virus is a birnavirus that causes an acute, contagious disease in young salmonid fish.
References
- ↑ Manning, D.S.; Leong, J.C. (1990). "Expression in Escherichia coli of the large genomic segment of infectious pancreatic necrosis virus". Virology. 179: 16–25. doi:10.1016/0042-6822(90)90268-v. PMID 2219718.
- ↑ Petit, S.; Lejal, N.; Huet, J.C.; Delmas, B. (2000). "Active residues and viral substrate cleavage sites of the protease of the birnavirus infectious pancreatic necrosis virus". J. Virol. 74: 2057–2066. doi:10.1128/jvi.74.5.2057-2066.2000. PMID 10666235.
- ↑ Dobos, P. (1995). "The molecular biology of infectious pancreatic necrosis virus (IPNV)". Annu. Rev. Fish Dis. 5: 25–54. doi:10.1016/0959-8030(95)00003-8.
External links
- Infectious pancreatic necrosis birnavirus Vp4 peptidase at the US National Library of Medicine Medical Subject Headings (MeSH)
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