Pegaspargase
Clinical data | |
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AHFS/Drugs.com | Monograph |
MedlinePlus | a695031 |
Pregnancy category |
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ATC code | L01XX24 (WHO) |
Legal status | |
Legal status |
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Identifiers | |
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CAS Number | 130167-69-0 |
DrugBank | DB00059 |
ChemSpider | none |
UNII | 7D96IR0PPM |
Chemical and physical data | |
Formula | C1377H2208N382O442S17 |
Molar mass | 31731.9 g/mol |
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Pegaspargase /pəˈɡæspərɡeɪz/, trade name Oncaspar, is a modified enzyme used as an antineoplastic agent. It is a form of L-asparaginase[1] which has undergone PEGylation.
It is used in the treatment of acute lymphoblastic leukemia.[2][3]
See also
References
- ↑ "UNM Cancer Center". Archived from the original on September 3, 2006. Retrieved 2007-08-28.
- ↑ Graham ML (2003). "Pegaspargase: a review of clinical studies". Adv. Drug Deliv. Rev. 55 (10): 1293–302. doi:10.1016/S0169-409X(03)00110-8. PMID 14499708.
- ↑ Patel SS, Benfield P (Jun 1996). "New drug profile: pegaspargase (Polyethylene Glycol L-Asparaginase)". Clinical Immunotherapeutics. 5 (6): 492–496.
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