2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene

2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene

Identifiers
IUPAC name 2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene
Chemical and physical data
Formula	C25H40O2
Molar mass	372.582 g/mol
3D model (Jmol)	Interactive image
SMILES CC(C)C=2CCC(C)CC=2c1c(O)cc(cc1O)CCCCCCCCC
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2-Isopropyl-5-methyl-1-(2,6-dihydroxy-4-nonylphenyl)cyclohex-1-ene is an analgesic compound that is a cannabinoid agonist. It is a ring-opened cannabinoid derivative, an analogue of cannabidiol. However, unlike cannabidiol, this compound produces potent cannabis-like effects in animals, suggesting it acts as a CB₁ agonist.^[1]

It can be synthesized by Birch reduction from the nonyl-analog of cannabidiol.^[2]

References

1. Razdan, K. (1981). "The Total Synthesis of Cannabinoids". In John Apsimon. The Total Synthesis of Natural Products. Wiley Interscience. p. 245. ISBN 978-0-471-05460-3. OCLC 19487018.
2. Razdan RK, Pars HG, Thompson WR, Granchelli FE (1974). "Lithium-ammonia reduction of tetrahydrocannabinols". Tetrahedron Letters. 15 (49–50): 4315. doi:10.1016/S0040-4039(01)92152-5.