Fanetizole

Fanetizole
Pharmacokinetic data
Protein binding %
Identifiers
CAS Number 79069-94-6
PubChem (CID) 54339
ChemSpider 49083
UNII BH48F620JA YesY
Chemical and physical data
Formula C17H16N2S
Molar mass 280.39 g/mol
3D model (Jmol) Interactive image
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Fanetizole shows immunoregulating activity.

Synthesis

Thioureas serve as a convenient starting material for 2-aminothiazoles.

Fanetizole synthesis:[1]

Reaction of β-phenethylamine with ammonium isothiocyanate gives the thiourea (2) Treatment of that product with phenacyl bromide thus affords the thiazole product.

References

  1. Lombardino, J. G.; 1981, U.S. Patent 4,307,106
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