Acecarbromal
 | |
| Names | |
|---|---|
| IUPAC name
N-(Acetylcarbamoyl)-2-bromo-2-ethylbutanamide | |
| Other names
1-Acetyl-3-(2-bromo-2-ethylbutyryl)urea | |
| Identifiers | |
77-66-7  | |
| 3D model (Jmol) | Interactive image Interactive image |
| ChEMBL | ChEMBL2104673 |
| ChemSpider | 6244 |
| ECHA InfoCard | 100.000.953 |
| EC Number | 201-047-1 |
| KEGG | D07059 |
| MeSH | acecarbromal |
| PubChem | 6489 |
| UNII | E47C56IGOY |
| |
| |
| Properties | |
| C9H15BrN2O3 | |
| Molar mass | 279.13 g·mol−1 |
| Pharmacology | |
| Legal status |
|
| Oral | |
| Related compounds | |
| Related compounds |
|
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917[1] that was formerly marketed in the United States and Europe.[2][3] It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe.[4][5][6] Acecarbromal is structurally related to the barbiturates, which are basically cyclized ureas.[7] Prolonged use is not recommended as it can cause bromine poisoning.[7]
See also
References
- ↑ DE Patent 327129
- ↑ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 2–. ISBN 978-1-4757-2085-3.
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 4–. ISBN 978-3-88763-075-1.
- ↑ Muller (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 36–. ISBN 978-3-7692-2114-5.
- ↑ Baumbusch, F; Papp, GK; Kopa, ZS (1995). "Treatment for potency problems with Afrodor 2000". Acta chirurgica Hungarica. 35 (1–2): 87–92. PMID 8659243.
- ↑ Sperling, H; Lümmen, G; Luboldt, HJ; Rübben, H (1999). "Secondary erectile dysfunction. Is oral medication in the diagnostic phase indicated?". Der Urologe. Ausg. A. 38 (1): 56–9. doi:10.1007/s001200050246. PMID 10081103.
- 1 2 David A. Williams; William O. Foye; Thomas L. Lemke (January 2002). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 380–. ISBN 978-0-683-30737-5.
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