Fosfestrol

Fosfestrol

Clinical data
Trade names	Honvan
AHFS/Drugs.com	International Drug Names
ATC code	L02AA04 (WHO)
Legal status
Legal status	℞ (Prescription only)
Identifiers
IUPAC name [4-[4-(4-phosphonooxyphenyl)hex-3-en-3-yl] phenoxy]phosphonic acid
CAS Number	13425-53-1
PubChem (CID)	3032325
ChemSpider	2297327
UNII	A0E0NMA80F
KEGG	D00946
ChEMBL	CHEMBL1200598
ECHA InfoCard	100.007.573
Chemical and physical data
Formula	C18H22O8P2
Molar mass	428.310 g/mol
3D model (Jmol)	Interactive image
SMILES O=P(Oc1ccc(cc1)\C(=C(\c2ccc(OP(=O)(O)O)cc2)CC)CC)(O)O
InChI InChI=1S/C18H22O8P2/c1-3-17(13-5-9-15(10-6-13)25-27(19,20)21)18(4-2)14-7-11-16(12-8-14)26-28(22,23)24/h5-12H,3-4H2,1-2H3,(H2,19,20,21)(H2,22,23,24)/b18-17+ Key:NLORYLAYLIXTID-ISLYRVAYSA-N
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Fosfestrol (INN, BAN, JAN) (brand names Honvan, Difostilben, Fosfostilben, Fostrolin, Stilbol, Stilphostrol, Vagestrol, among others), also known as diethylstilbestrol diphosphate (USAN), abbreviated as DESDP or DESP, is a synthetic, non-steroidal estrogen of the stilbestrol group that is or has been used in the treatment of prostate cancer.^[1][2] It is a prodrug of diethylstilbestrol.^[3] The drug has been marketed widely throughout the world, including in the United States, Canada, Europe, Hong Kong, and Mexico.^[1]

See also

• Diethylstilbestrol dipropionate
• Dimestrol
• Furostilbestrol
• Mestilbol

References

1. Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 332–. ISBN 978-3-88763-075-1.
2. Shanbhag (1 January 2008). Pharmacology: Prep Manual for Undergraduates. Elsevier India. pp. 463–. ISBN 978-81-312-1153-3.
3. Urotext (1 January 2001). Urotext-Luts: Urology. Urotext. pp. 386–. ISBN 978-1-903737-03-3.